Amlodipinum [Latin]

Amlodipinum [Latin] Brand names, Amlodipinum [Latin] Analogs

Amlodipinum [Latin] Brand Names Mixture

Lotrel (amlodipine + benazepril)

Amlodipinum [Latin] Chemical_Formula

C₂₀H₂₅ClN₂O₅

Amlodipinum [Latin] RX_link

http://www.rxlist.com/cgi/generic/amlod2.htm

Amlodipinum [Latin] fda sheet

Amlodipinum [Latin] msds (material safety sheet)

Amlodipinum [Latin] Synthesis Reference

S. F. Campbell et al., U.S. Pat. 4,572,909 (1986)

Amlodipinum [Latin] Molecular Weight

408.876 g/mol

Amlodipinum [Latin] Melting Point

178-179^oC

Amlodipinum [Latin] H₂O Solubility

75.3 mg/L

Amlodipinum [Latin] State

Solid

Amlodipinum [Latin] LogP

2.347

Amlodipinum [Latin] Dosage Forms

Tablets (equivalent to 2.5, 5 and 10 mg)

Amlodipinum [Latin] Indication

For the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Amlodipinum [Latin] Pharmacology

Amlodipine, a calcium-channel blocker, is used alone or with benazepril, an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Amlodipine is similar to the peripheral vasodilator nifedipine and other members of the dihydropyridine class.

Amlodipinum [Latin] Absorption

Amlodipine is slowly and almost completely absorbed from the gastrointestinal tract.

Amlodipinum [Latin] side effects and Toxicity

Gross overdosage could result in excessive peripheral vasodilatation and possibly reflex tachycardia. Marked and probably prolonged systemic hypotension up to an including shock with fatal outcome have been reported.

Amlodipinum [Latin] Patient Information

Amlodipinum [Latin] Organisms Affected

Humans and other mammals